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UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions
Photochemotherapy, the combination of a photosensitiser and ultraviolet (UV) or visible light, is an effective treatment for skin conditions including cancer. The high mutagenicity and non-selectivity of photochemotherapy regimes warrants the development of alternative approaches. We demonstrate tha...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Sequoia
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376468/ https://www.ncbi.nlm.nih.gov/pubmed/25747491 http://dx.doi.org/10.1016/j.jphotobiol.2015.02.012 |