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Delta-Tocotrienol Suppresses Radiation-Induced MicroRNA-30 and Protects Mice and Human CD34+ Cells from Radiation Injury

We reported that microRNA-30c (miR-30c) plays a key role in radiation-induced human cell damage through an apoptotic pathway. Herein we further evaluated radiation-induced miR-30 expression and mechanisms of delta-tocotrienol (DT3), a radiation countermeasure candidate, for regulating miR-30 in a mo...

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Detalles Bibliográficos
Autores principales: Li, Xiang Hong, Ha, Cam T., Fu, Dadin, Landauer, Michael R., Ghosh, Sanchita P., Xiao, Mang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376529/
https://www.ncbi.nlm.nih.gov/pubmed/25815474
http://dx.doi.org/10.1371/journal.pone.0122258