Camalexin-Induced Apoptosis in Prostate Cancer Cells Involves Alterations of Expression and Activity of Lysosomal Protease Cathepsin D

Camalexin, the phytoalexin produced in the model plant Arabidopsis thaliana, possesses antiproliferative and cancer chemopreventive effects. We have demonstrated that the cytostatic/cytotoxic effects of camalexin on several prostate cancer (PCa) cells are due to oxidative stress. Lysosomes are vulne...

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Detalles Bibliográficos
Autores principales: Smith, Basil, Randle, Diandra, Mezencev, Roman, Thomas, LeeShawn, Hinton, Cimona, Marah, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376535/
https://www.ncbi.nlm.nih.gov/pubmed/24699144
http://dx.doi.org/10.3390/molecules19043988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376535/
https://www.ncbi.nlm.nih.gov/pubmed/24699144
http://dx.doi.org/10.3390/molecules19043988

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