Cargando…

Ethanol Exposure Induces Neonatal Neurodegeneration by Enhancing CB1R Exon1 Histone H4K8 Acetylation and Up-regulating CB1R Function causing Neurobehavioral Abnormalities in Adult Mice

BACKGROUND: Ethanol exposure to rodents during postnatal day 7 (P7), which is comparable to the third trimester of human pregnancy, induces long-term potentiation and memory deficits. However, the molecular mechanisms underlying these deficits are still poorly understood. METHODS: In the present stu...

Descripción completa

Detalles Bibliográficos
Autores principales: Subbanna, Shivakumar, Nagre, Nagaraja N., Umapathy, Nagavedi S., Pace, Betty S., Basavarajappa, Balapal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376538/
https://www.ncbi.nlm.nih.gov/pubmed/25609594
http://dx.doi.org/10.1093/ijnp/pyu028