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Ethanol Exposure Induces Neonatal Neurodegeneration by Enhancing CB1R Exon1 Histone H4K8 Acetylation and Up-regulating CB1R Function causing Neurobehavioral Abnormalities in Adult Mice
BACKGROUND: Ethanol exposure to rodents during postnatal day 7 (P7), which is comparable to the third trimester of human pregnancy, induces long-term potentiation and memory deficits. However, the molecular mechanisms underlying these deficits are still poorly understood. METHODS: In the present stu...
Autores principales: | Subbanna, Shivakumar, Nagre, Nagaraja N., Umapathy, Nagavedi S., Pace, Betty S., Basavarajappa, Balapal S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376538/ https://www.ncbi.nlm.nih.gov/pubmed/25609594 http://dx.doi.org/10.1093/ijnp/pyu028 |
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