Cargando…

Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease

Cyclic guanosine monophosphate (cGMP) is a second messenger molecule that transduces nitric oxide (NO) and natriuretic peptide (NP) coupled signaling, stimulating phosphorylation changes by protein kinase G (PKG). Enhancing cGMP synthesis or blocking its degradation by phosphodiesterase type 5A (PDE...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Dong I., Zhu, Guangshuo, Sasaki, Takashi, Cho, Gun-Sik, Hamdani, Nazha, Holewinski, Ronald, Jo, Su-Hyun, Danner, Thomas, Zhang, Manling, Rainer, Peter P., Bedja, Djahida, Kirk, Jonathan A., Ranek, Mark J., Dostmann, Wolfgang R., Kwon, Chulan, Margulies, Kenneth B., Van Eyk, Jennifer E., Paulus, Walter J., Takimoto, Eiki, Kass, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376609/ https://www.ncbi.nlm.nih.gov/pubmed/25799991 http://dx.doi.org/10.1038/nature14332

Ejemplares similares

Transient kinetics of a cGMP-dependent cGMP-specific phosphodiesterase from Dictyostelium discoideum
Publicado: (1984)

cGMP Signaling, Phosphodiesterases and Major Depressive Disorder
por: Reierson, Gillian W, et al.
Publicado: (2011)

In situ cGMP phosphodiesterase and photoreceptor potential in gecko retina
Publicado: (1986)

cGMP-PKG upregulates PGC1α and improves cardiac function in advanced cardiac hypertrophy independently of RGS2
por: Takimoto, Eiki
Publicado: (2011)

Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication
por: Dostmann, Wolfgang R, et al.
Publicado: (2011)

The cGMP-phosphodiesterase and its contribution to sensitivity regulation in retinal rods
Publicado: (1995)

Sub-Nanomolar Sensitivity of Nitric Oxide Mediated Regulation of cGMP and Vasomotor Reactivity in Vascular Smooth Muscle
por: Held, Kara F., et al.
Publicado: (2012)

It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods
por: Qureshi, Bilal M., et al.
Publicado: (2018)

Determination of basal phosphodiesterase activity in mouse rod photoreceptors with cGMP clamp
por: Turunen, Teemu T., et al.
Publicado: (2019)

Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases
por: Kopra, Kari, et al.
Publicado: (2020)

A structural analysis of the regulatory domain from the cGMP-dependent protein kinase Iα
por: Osborne, Brent W, et al.
Publicado: (2011)

PKG-Modified TSC2 Regulates mTORC1 Activity to Counter Adverse Cardiac Stress
por: Ranek, Mark J., et al.
Publicado: (2019)

Phosphodiesterase 9A in Brain Regulates cGMP Signaling Independent of Nitric-Oxide
por: Harms, John F., et al.
Publicado: (2019)

Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in Toxoplasma gondii
por: Vo, Kim Chi, et al.
Publicado: (2022)

Long-term potentiation in hippocampus involves sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase and cGMP-degrading phosphodiesterase, alterations in hyperammonemia
por: Monfort, Pilar, et al.
Publicado: (2005)

Increased Energy Expenditure and Protection From Diet-Induced Obesity in Mice Lacking the cGMP-Specific Phosphodiesterase PDE9
por: Ceddia, Ryan P., et al.
Publicado: (2021)

cGMP-Phosphodiesterase Inhibition Enhances Photic Responses and Synchronization of the Biological Circadian Clock in Rodents
por: Plano, Santiago A., et al.
Publicado: (2012)

Asymmetric properties of rod cGMP Phosphodiesterase 6 (PDE6): structural and functional analysis
por: Qureshi, Bilal M, et al.
Publicado: (2015)

Short- and Long-Term Effects of UVA on Arabidopsis Are Mediated by a Novel cGMP Phosphodiesterase
por: Isner, Jean-Charles, et al.
Publicado: (2019)

Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia
por: Bork, Nadja I., et al.
Publicado: (2021)

cGMP-dependent protein kinase from Toxoplasma gondii: functional expression in E. coli and molecular characterization
por: McFarland, Caitlin J, et al.
Publicado: (2011)

Concerted Regulation of cGMP and cAMP Phosphodiesterases in Early Cardiac Hypertrophy Induced by Angiotensin II
por: Mokni, Walid, et al.
Publicado: (2010)

cGMP-Phosphodiesterase Inhibition Prevents Hypoxia-Induced Cell Death Activation in Porcine Retinal Explants
por: Olivares-González, Lorena, et al.
Publicado: (2016)

Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum
por: Dhaunsi, Gursev S., et al.
Publicado: (2017)

Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts
por: Calamera, Gaia, et al.
Publicado: (2022)

NO/cGMP signalling in platelets
por: Schinner, Elisabeth, et al.
Publicado: (2009)

cGMP and cardiac hypertrophy
por: Perera, Ruwan K, et al.
Publicado: (2015)

Analysis of cGMP signalling with transgenic mice expressing FRET-based cGMP sensors
por: Wen, Lai, et al.
Publicado: (2013)

Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure
por: Baliga, Reshma S., et al.
Publicado: (2018)

Neuralized family member NEURL1 is a ubiquitin ligase for the cGMP-specific phosphodiesterase 9A
por: Taal, Kati, et al.
Publicado: (2019)

Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection
por: Foulke-Abel, Jennifer, et al.
Publicado: (2020)

Upregulation of Phosphodiesterase 2A Augments T Cell Activation by Changing cGMP/cAMP Cross-Talk
por: Kurelic, Roberta, et al.
Publicado: (2021)

Cyclic GMP and PKG Signaling in Heart Failure
por: Numata, Genri, et al.
Publicado: (2022)

Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling
por: Mullershausen, Florian, et al.
Publicado: (2003)

Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling
por: Hashimoto, Toru, et al.
Publicado: (2016)

Transducin activates cGMP phosphodiesterase by trapping inhibitory γ subunit freed reversibly from the catalytic subunit in solution
por: Asano, Teizo, et al.
Publicado: (2019)

The Delta Subunit of Rod-Specific Photoreceptor cGMP Phosphodiesterase (PDE6D) Contributes to Hepatocellular Carcinoma Progression
por: Dietrich, Peter, et al.
Publicado: (2019)

PDE5 says NO to cGMP
por: LeBrasseur, Nicole
Publicado: (2003)

cGMP steers axons home
por: LeBrasseur, Nicole
Publicado: (2002)

A novel pathway of cGMP
por: Kuhn, Michaela, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_d6mreif0mp2trb2tu5j9rofpl0