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Mitochondrial Control by DRP1 in Brain Tumor Initiating Cells

Brain tumor initiating cells (BTICs) coopt the neuronal high affinity GLUT3 glucose transporter to withstand metabolic stress. Here, we investigated another mechanism critical to brain metabolism, mitochondrial morphology. BTICs displayed mitochondrial fragmentation relative to non-BTICs, suggesting...

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Detalles Bibliográficos
Autores principales: Xie, Qi, Wu, Qiulian, Horbinski, Craig M., Flavahan, William A., Yang, Kailin, Zhou, Wenchao, Dombrowski, Stephen M., Huang, Zhi, Fang, Xiaoguang, Shi, Yu, Ferguson, Ashley N., Kashatus, David F., Bao, Shideng, Rich, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376639/
https://www.ncbi.nlm.nih.gov/pubmed/25730670
http://dx.doi.org/10.1038/nn.3960