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Mitochondrial Control by DRP1 in Brain Tumor Initiating Cells
Brain tumor initiating cells (BTICs) coopt the neuronal high affinity GLUT3 glucose transporter to withstand metabolic stress. Here, we investigated another mechanism critical to brain metabolism, mitochondrial morphology. BTICs displayed mitochondrial fragmentation relative to non-BTICs, suggesting...
Autores principales: | Xie, Qi, Wu, Qiulian, Horbinski, Craig M., Flavahan, William A., Yang, Kailin, Zhou, Wenchao, Dombrowski, Stephen M., Huang, Zhi, Fang, Xiaoguang, Shi, Yu, Ferguson, Ashley N., Kashatus, David F., Bao, Shideng, Rich, Jeremy N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376639/ https://www.ncbi.nlm.nih.gov/pubmed/25730670 http://dx.doi.org/10.1038/nn.3960 |
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