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Frequency and Geographic Distribution of gyrA and gyrB Mutations Associated with Fluoroquinolone Resistance in Clinical Mycobacterium Tuberculosis Isolates: A Systematic Review

BACKGROUND: The detection of mutations in the gyrA and gyrB genes in the Mycobacterium tuberculosis genome that have been demonstrated to confer phenotypic resistance to fluoroquinolones is the most promising technology for rapid diagnosis of fluoroquinolone resistance. METHODS: In order to characte...

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Detalles Bibliográficos
Autores principales: Avalos, Elisea, Catanzaro, Donald, Catanzaro, Antonino, Ganiats, Theodore, Brodine, Stephanie, Alcaraz, John, Rodwell, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376704/
https://www.ncbi.nlm.nih.gov/pubmed/25816236
http://dx.doi.org/10.1371/journal.pone.0120470