An Essential Signal Peptide Peptidase Identified in an RNAi Screen of Serine Peptidases of Trypanosoma brucei

The serine peptidases of Trypanosoma brucei have been viewed as potential drug targets. In particular, the S9 prolyl oligopeptidase subfamily is thought to be a good avenue for drug discovery. This is based on the finding that some S9 peptidases are secreted and active in the mammalian bloodstream,...

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Detalles Bibliográficos
Autores principales: Moss, Catherine X., Brown, Elaine, Hamilton, Alana, Van der Veken, Pieter, Augustyns, Koen, Mottram, Jeremy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376731/
https://www.ncbi.nlm.nih.gov/pubmed/25816352
http://dx.doi.org/10.1371/journal.pone.0123241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376731/
https://www.ncbi.nlm.nih.gov/pubmed/25816352
http://dx.doi.org/10.1371/journal.pone.0123241

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