Lipopolysaccharide-Induced Middle Ear Inflammation Disrupts the cochlear Intra-Strial Fluid–Blood Barrier through Down-Regulation of Tight Junction Proteins

Middle ear infection (or inflammation) is the most common pathological condition that causes fluid to accumulate in the middle ear, disrupting cochlear homeostasis. Lipopolysaccharide, a product of bacteriolysis, activates macrophages and causes release of inflammatory cytokines. Many studies have s...

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Detalles Bibliográficos
Autores principales: Zhang, Jinhui, Chen, Songlin, Hou, Zhiqiang, Cai, Jing, Dong, Mingmin, Shi, Xiaorui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376743/
https://www.ncbi.nlm.nih.gov/pubmed/25815897
http://dx.doi.org/10.1371/journal.pone.0122572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376743/
https://www.ncbi.nlm.nih.gov/pubmed/25815897
http://dx.doi.org/10.1371/journal.pone.0122572

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