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Enhanced Hepatogenic Transdifferentiation of Human Adipose Tissue Mesenchymal Stem Cells by Gene Engineering with Oct4 and Sox2

Adipose tissue mesenchymal stem cells (ATMSCs) represent an attractive tool for the establishment of a successful stem cell-based therapy in the field of liver regeneration medicine. ATMSCs overexpressing Oct4 and Sox2 (Oct4/Sox2-ATMSCs) showed enhanced proliferation and multipotency. Hence, we hypo...

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Detalles Bibliográficos
Autores principales: Han, Sei-Myoung, Coh, Ye-Rin, Ahn, Jin-Ok, Jang, Goo, Yum, Soo Young, Kang, Sung-Keun, Lee, Hee-Woo, Youn, Hwa-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376765/
https://www.ncbi.nlm.nih.gov/pubmed/25815812
http://dx.doi.org/10.1371/journal.pone.0108874