α7 Nicotinic Acetylcholine Receptor-Specific Antibody Induces Inflammation and Amyloid β(42) Accumulation in the Mouse Brain to Impair Memory

Nicotinic acetylcholine receptors (nAChRs) expressed in the brain are involved in regulating cognitive functions, as well as inflammatory reactions. Their density is decreased upon Alzheimer disease accompanied by accumulation of β-amyloid (Aβ(42)), memory deficit and neuroinflammation. Previously w...

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Detalles Bibliográficos
Autores principales: Lykhmus, Olena, Voytenko, Larysa, Koval, Lyudmyla, Mykhalskiy, Sergiy, Kholin, Victor, Peschana, Kateryna, Zouridakis, Marios, Tzartos, Socrates, Komisarenko, Sergiy, Skok, Maryna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376778/
https://www.ncbi.nlm.nih.gov/pubmed/25816313
http://dx.doi.org/10.1371/journal.pone.0122706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376778/
https://www.ncbi.nlm.nih.gov/pubmed/25816313
http://dx.doi.org/10.1371/journal.pone.0122706

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