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The Impact of Immunosenescence on Humoral Immune Response Variation after Influenza A/H1N1 Vaccination in Older Subjects

BACKGROUND: Although influenza causes significant morbidity and mortality in the elderly, the factors underlying the reduced vaccine immunogenicity and efficacy in this age group are not completely understood. Age and immunosenescence factors, and their impact on humoral immunity after influenza vac...

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Detalles Bibliográficos
Autores principales: Haralambieva, Iana H., Painter, Scott D., Kennedy, Richard B., Ovsyannikova, Inna G., Lambert, Nathaniel D., Goergen, Krista M., Oberg, Ann L., Poland, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376784/
https://www.ncbi.nlm.nih.gov/pubmed/25816015
http://dx.doi.org/10.1371/journal.pone.0122282