Synergistic Interactions between Drosophila Orthologues of Genes Spanned by De Novo Human CNVs Support Multiple-Hit Models of Autism

Autism spectrum disorders (ASDs) are highly heritable and characterised by deficits in social interaction and communication, as well as restricted and repetitive behaviours. Although a number of highly penetrant ASD gene variants have been identified, there is growing evidence to support a causal ro...

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Detalles Bibliográficos
Autores principales: Grice, Stuart J., Liu, Ji-Long, Webber, Caleb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376901/
https://www.ncbi.nlm.nih.gov/pubmed/25816101
http://dx.doi.org/10.1371/journal.pgen.1004998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376901/
https://www.ncbi.nlm.nih.gov/pubmed/25816101
http://dx.doi.org/10.1371/journal.pgen.1004998

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