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Cardiovascular Toxicity of Multi-Tyrosine Kinase Inhibitors in Advanced Solid Tumors: A Population-Based Observational Study

BACKGROUND: Treatment with small molecule tyrosine kinase inhibitors (TKIs) has improved survival in many cancers, yet has been associated with an increased risk of adverse events. Warnings of cardiovascular events are common in drug labels of many TKIs. Despite these warnings, cardiovascular toxici...

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Detalles Bibliográficos
Autores principales: Srikanthan, Amirrtha, Ethier, Josee-Lyne, Ocana, Alberto, Seruga, Bostjan, Krzyzanowska, Monika K., Amir, Eitan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376902/
https://www.ncbi.nlm.nih.gov/pubmed/25815472
http://dx.doi.org/10.1371/journal.pone.0122735