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Gut Microbiota and Tacrolimus Dosing in Kidney Transplantation

Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a challenging task because of much interpatient and intrapatient variability in drug absorption, metabolism, and disposition. In view of the reported impact of gut microbial species on drug metabolism, we investi...

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Detalles Bibliográficos
Autores principales: Lee, John R., Muthukumar, Thangamani, Dadhania, Darshana, Taur, Ying, Jenq, Robert R., Toussaint, Nora C., Ling, Lilan, Pamer, Eric, Suthanthiran, Manikkam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376942/
https://www.ncbi.nlm.nih.gov/pubmed/25815766
http://dx.doi.org/10.1371/journal.pone.0122399