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Gut Microbiota and Tacrolimus Dosing in Kidney Transplantation
Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a challenging task because of much interpatient and intrapatient variability in drug absorption, metabolism, and disposition. In view of the reported impact of gut microbial species on drug metabolism, we investi...
Autores principales: | Lee, John R., Muthukumar, Thangamani, Dadhania, Darshana, Taur, Ying, Jenq, Robert R., Toussaint, Nora C., Ling, Lilan, Pamer, Eric, Suthanthiran, Manikkam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376942/ https://www.ncbi.nlm.nih.gov/pubmed/25815766 http://dx.doi.org/10.1371/journal.pone.0122399 |
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