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Efficacy and Safety of Linagliptin Co-Administered with Low-Dose Metformin Once Daily Versus High-Dose Metformin Twice Daily in Treatment-Naïve Patients with Type 2 Diabetes: a Double-Blind Randomized Trial

INTRODUCTION: The aim of this study was to investigate the efficacy and safety of linagliptin + low-dose (LD) metformin once daily versus high-dose (HD) metformin twice daily in treatment-naïve patients with type 2 diabetes. METHODS: Patients (n = 689) were randomized (1:1) to double-blind treatment...

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Detalles Bibliográficos
Autores principales: Ji, Linong, Zinman, Bernard, Patel, Sanjay, Ji, Jinfeng, Bailes, Zelie, Thiemann, Sandra, Seck, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376958/
https://www.ncbi.nlm.nih.gov/pubmed/25805187
http://dx.doi.org/10.1007/s12325-015-0195-3