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Nop17 is a key R2TP factor for the assembly and maturation of box C/D snoRNP complex

BACKGROUND: Box C/D snoRNPs are responsible for rRNA methylation and processing, and are formed by snoRNAs and four conserved proteins, Nop1, Nop56, Nop58 and Snu13. The snoRNP assembly is a stepwise process, involving other protein complexes, among which the R(2)TP and Hsp90 chaperone. Nop17, also...

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Detalles Bibliográficos
Autores principales: Prieto, Marcela B, Georg, Raphaela C, Gonzales-Zubiate, Fernando A, Luz, Juliana S, Oliveira, Carla C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377001/
https://www.ncbi.nlm.nih.gov/pubmed/25888478
http://dx.doi.org/10.1186/s12867-015-0037-5