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Effects of oxonic acid-induced hyperuricemia on mesenteric artery tone and cardiac load in experimental renal insufficiency

BACKGROUND: Recent studies suggest a causal role for increased plasma uric acid in the progression of chronic renal insufficiency (CRI). However, uric acid also functions as an antioxidant with possible beneficial effects. METHODS: We investigated the influence of hyperuricemia on mesenteric arteria...

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Detalles Bibliográficos
Autores principales: Kurra, Venla, Vehmas, Tuija, Eräranta, Arttu, Jokihaara, Jarkko, Pirttiniemi, Päivi, Ruskoaho, Heikki, Tokola, Heikki, Niemelä, Onni, Mustonen, Jukka, Pörsti, Ilkka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377065/
https://www.ncbi.nlm.nih.gov/pubmed/25886588
http://dx.doi.org/10.1186/s12882-015-0033-5