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Impact of EPA ingestion on COX- and LOX-mediated eicosanoid synthesis in skin with and without a pro-inflammatory UVR challenge – Report of a randomised controlled study in humans

SCOPE: Eicosapentaenoic acid (EPA), abundant in oily fish, is reported to reduce skin inflammation and provide photoprotection, potential mechanisms include competition with arachidonic acid (AA) for metabolism by cyclooxygenases/lipoxygenases to less pro-inflammatory mediators. We thus examine impa...

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Detalles Bibliográficos
Autores principales: Pilkington, Suzanne M, Rhodes, Lesley E, Al-Aasswad, Naser M I, Massey, Karen A, Nicolaou, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377077/
https://www.ncbi.nlm.nih.gov/pubmed/24311515
http://dx.doi.org/10.1002/mnfr.201300405