Cargando…

Impact of EPA ingestion on COX- and LOX-mediated eicosanoid synthesis in skin with and without a pro-inflammatory UVR challenge – Report of a randomised controlled study in humans

SCOPE: Eicosapentaenoic acid (EPA), abundant in oily fish, is reported to reduce skin inflammation and provide photoprotection, potential mechanisms include competition with arachidonic acid (AA) for metabolism by cyclooxygenases/lipoxygenases to less pro-inflammatory mediators. We thus examine impa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pilkington, Suzanne M, Rhodes, Lesley E, Al-Aasswad, Naser M I, Massey, Karen A, Nicolaou, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377077/ https://www.ncbi.nlm.nih.gov/pubmed/24311515 http://dx.doi.org/10.1002/mnfr.201300405

Ejemplares similares

Thiazoles and Thiazolidinones as COX/LOX Inhibitors
por: Liaras, Konstantinos, et al.
Publicado: (2018)

Melanoma-associated repair-like Schwann cells suppress anti-tumor T-cells via 12/15-LOX/COX2-associated eicosanoid production
por: Kruglov, Oleg, et al.
Publicado: (2023)

COX inhibition reduces vasodilator PGE(2) but is shown to increase levels of chemoattractant 12‐HETE in vivo in human sunburn
por: Pilkington, Suzanne M., et al.
Publicado: (2015)

A randomised feasibility study of EPA and Cox-2 inhibitor (Celebrex) versus EPA, Cox-2 inhibitor (Celebrex), Resistance Training followed by ingestion of essential amino acids high in leucine in NSCLC cachectic patients - ACCeRT Study
por: Rogers, Elaine S, et al.
Publicado: (2011)

Eicosanoids metabolized through LOX distinguish asthma–COPD overlap from COPD by metabolomics study
por: Cai, Chuanxu, et al.
Publicado: (2019)

The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases
por: Rhodes, Lesley E., et al.
Publicado: (2009)

{OElig}uvres
por: Rimbaud, Arthur, 1854-1891
Publicado: (1950)

Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor
por: Athira, A. P., et al.
Publicado: (2013)

Eicosanoids in Skin Wound Healing
por: Yasukawa, Ken, et al.
Publicado: (2020)

Effects of Enriched Environment on COX-2, Leptin and Eicosanoids in a Mouse Model of Breast Cancer
por: Nachat-Kappes, Rachida, et al.
Publicado: (2012)

Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB–DNA complexes
por: Webster, Matthew P. J., et al.
Publicado: (2012)

Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma
por: Rao, Chinthalapally V., et al.
Publicado: (2015)

{OElig}uvres complétes
por: Lamartine, Alphonse de, 1790-1869
Publicado: (1834)

{OElig}uvres chorales
por: Brossard, Sébastien de, d. 1730
Publicado: (1997)

{OElig}uvres complétes
por: Barraqué, Jean
Publicado: (1998)

{OElig}uvres complétes /
por: Pascal, Blaise, 1623-1662
Publicado: (1998)

{OElig}uvres complétes /
por: Lautréamont, conde de, 1846-1870
Publicado: (1970)

{OElig}uvres complétes /
por: Nerval, Gérard de, 1808-1855
Publicado: (1989)

L'{oelig}uvre /
por: Zola, Émile, 1840-1902
Publicado: (1983)

{OElig}uvres complétes
por: Domenichino, 1581-1641
Publicado: (1864)

Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin
por: Crescente, Marilena, et al.
Publicado: (2020)

The association of eicosanoids and eicosanoid-related metabolites with pulmonary hypertension
por: McNeill, Jenna N., et al.
Publicado: (2023)

The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1
por: Crowley, David J, et al.
Publicado: (2006)

Enhancement of ATRA-induced differentiation of neuroblastoma cells with LOX/COX inhibitors: an expression profiling study
por: Chlapek, Petr, et al.
Publicado: (2010)

The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression
por: Chlapek, Petr, et al.
Publicado: (2014)

A Metabolomic Approach to Target Compounds from the Asteraceae Family for Dual COX and LOX Inhibition
por: Chagas-Paula, Daniela A., et al.
Publicado: (2015)

Evidence for using a dual COX 1/2 and 5-LOX inhibitor in neurodegenerative diseases
por: Irrera, Natasha, et al.
Publicado: (2017)

Biological Evaluation of Naproxen–Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors
por: Moreira, Rute, et al.
Publicado: (2020)

Pro-oncogenic action of LOX-1 and its splice variant LOX-1Δ4 in breast cancer phenotypes
por: Pucci, Sabina, et al.
Publicado: (2019)

Eicosanoids in reproduction /
Publicado: (1990)

Eicosanoids and cancer
por: Gomes, Renata Nascimento, et al.
Publicado: (2018)

Genomic, Lipidomic and Metabolomic Analysis of Cyclooxygenase-null Cells: Eicosanoid Storm, Cross Talk, and Compensation by COX-1
por: Islam, Abul B.M.M.K., et al.
Publicado: (2016)

{OElig}uvres pour 2 pianos {OElig}uvres pour piano /
por: Poulenc, Francis, 1899-1963
Publicado: (1991)

{OElig}uvres romanesques complétes /
por: Aragon, 1897-
Publicado: (1997)

{OElig}uvres poétiques complétes /
por: Supervielle, Jules, 1884-1960
Publicado: (1996)

Oe{OElig}uvres complétes /
por: Mallarmé, Stéphane, 1842-1898
Publicado: (1989)

{OElig}uvres poétiques complétes /
por: Verlaine, Paul, 1844-1896
Publicado: (1992)

Dual COX and 5-LOX inhibition by clerodane diterpenes from seeds of Polyalthia longifolia (Sonn.) Thwaites
por: Nguyen, Ha Thi, et al.
Publicado: (2020)

Synthesis, Evaluation of Enzyme Inhibition and Redox Properties of Potential Dual COX-2 and 5-LOX Inhibitors
por: Bošković, Jelena, et al.
Publicado: (2023)

Expression of COX-1, COX-2, 5-LOX and [Formula: see text] in nasal polyps and bronchial tissue of patients with aspirin exacerbated airway disease
por: Vorsprach, Monique, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b8cii5496s85h0cu0dl62mok53