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Dysfunction of Endothelial Progenitor Cells from Smokers and Chronic Obstructive Pulmonary Disease Patients Due to Increased DNA Damage and Senescence

Cardiovascular disease (CVD) is a major cause of death in smokers, particularly in those with chronic obstructive pulmonary disease (COPD). Circulating endothelial progenitor cells (EPC) are required for endothelial homeostasis, and their dysfunction contributes to CVD. To investigate EPC dysfunctio...

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Detalles Bibliográficos
Autores principales: Paschalaki, Koralia E, Starke, Richard D, HU, Yanhua, Mercado, Nicolas, Margariti, Andriana, Gorgoulis, Vassilis G, Randi, Anna M, Barnes, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377082/
https://www.ncbi.nlm.nih.gov/pubmed/23897750
http://dx.doi.org/10.1002/stem.1488