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Dysfunction of Endothelial Progenitor Cells from Smokers and Chronic Obstructive Pulmonary Disease Patients Due to Increased DNA Damage and Senescence
Cardiovascular disease (CVD) is a major cause of death in smokers, particularly in those with chronic obstructive pulmonary disease (COPD). Circulating endothelial progenitor cells (EPC) are required for endothelial homeostasis, and their dysfunction contributes to CVD. To investigate EPC dysfunctio...
Autores principales: | Paschalaki, Koralia E, Starke, Richard D, HU, Yanhua, Mercado, Nicolas, Margariti, Andriana, Gorgoulis, Vassilis G, Randi, Anna M, Barnes, Peter J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377082/ https://www.ncbi.nlm.nih.gov/pubmed/23897750 http://dx.doi.org/10.1002/stem.1488 |
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