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Helicobacter hepaticus infection in BALB/c mice abolishes subunit-vaccine-induced protection against M. tuberculosis

BCG, the only licensed vaccine against tuberculosis (TB), provides geographically variable protection, an effect ascribed to exposure to environmental mycobacteria (EM). Here we show that altering the intestinal microbiota of mice by early-life infection with the commensal bacterium Helicobacter hep...

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Detalles Bibliográficos
Autores principales: Arnold, Isabelle C., Hutchings, Claire, Kondova, Ivanela, Hey, Ariann, Powrie, Fiona, Beverley, Peter, Tchilian, Elma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377097/
https://www.ncbi.nlm.nih.gov/pubmed/25748336
http://dx.doi.org/10.1016/j.vaccine.2015.02.041