BRCA1 germline mutation and glioblastoma development: report of cases

BACKGROUND: Germline mutations in breast cancer susceptibility gene 1 (BRCA1) increase the risk of breast and ovarian cancers. However, no association between BRCA1 germline mutation and glioblastoma malignancy has ever been highlighted. Here we report two cases of BRCA1 mutated patients who develop...

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Detalles Bibliográficos
Autores principales: Boukerroucha, Meriem, Josse, Claire, Segers, Karin, El-Guendi, Sonia, Frères, Pierre, Jerusalem, Guy, Bours, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377178/
https://www.ncbi.nlm.nih.gov/pubmed/25880076
http://dx.doi.org/10.1186/s12885-015-1205-1