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Robust network structure of the Sln1-Ypd1-Ssk1 three-component phospho-relay prevents unintended activation of the HOG MAPK pathway in Saccharomyces cerevisiae

BACKGROUND: The yeast Saccharomyces cerevisiae relies on the high-osmolarity glycerol (HOG) signaling pathway to respond to increases in external osmolarity. The HOG pathway is rapidly activated under conditions of elevated osmolarity and regulates transcriptional and metabolic changes within the ce...

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Detalles Bibliográficos
Autores principales: Dexter, Joseph P, Xu, Ping, Gunawardena, Jeremy, McClean, Megan N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377207/
https://www.ncbi.nlm.nih.gov/pubmed/25888817
http://dx.doi.org/10.1186/s12918-015-0158-y