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Properties and kinetics of microRNA regulation through canonical seed sites

MicroRNAs are a fundamental class of small RNAs involved in post-transcriptional gene regulation; however, the mechanism by which microRNAs regulate their gene targets in animals remains poorly understood. Practically, a mechanistic understanding of microRNA binding and regulation is crucial for the...

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Detalles Bibliográficos
Autores principales: Chen, Jerry S, Revilla, Arra C, Guerrero, Michael, Gumbayan, Abygail M, Zeller, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of RNAi and Gene Silencing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377283/
https://www.ncbi.nlm.nih.gov/pubmed/25870651