Loss of AMP-Activated Protein Kinase Induces Mitochondrial Dysfunction and Proinflammatory Response in Unstimulated Abcd1-Knockout Mice Mixed Glial Cells

X-linked adrenoleukodystrophy (X-ALD) is caused by mutations and/or deletions in the ABCD1 gene. Similar mutations/deletions can give rise to variable phenotypes ranging from mild adrenomyeloneuropathy (AMN) to inflammatory fatal cerebral adrenoleukodystrophy (ALD) via unknown mechanisms. We recentl...

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Detalles Bibliográficos
Autores principales: Singh, Jaspreet, Suhail, Hamid, Giri, Shailendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377497/
https://www.ncbi.nlm.nih.gov/pubmed/25861159
http://dx.doi.org/10.1155/2015/176983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377497/
https://www.ncbi.nlm.nih.gov/pubmed/25861159
http://dx.doi.org/10.1155/2015/176983

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