Cargando…

Zwitterionic Poly(carboxybetaine)-based Cationic Liposomes for Effective Delivery of Small Interfering RNA Therapeutics without Accelerated Blood Clearance Phenomenon

For efficient delivery of small interfering RNA (siRNA) to the target diseased site in vivo, it is important to design suitable vehicles to control the blood circulation of siRNA. It has been shown that surface modification of cationic liposome/siRNA complexes (lipoplexes) with polyethylene glycol (...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yan, Liu, Ruiyuan, Shi, Yuanjie, Zhang, Zhenzhong, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377727/
https://www.ncbi.nlm.nih.gov/pubmed/25825598
http://dx.doi.org/10.7150/thno.11234