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Down-Regulation of miR-129-5p and the let-7 Family in Neuroendocrine Tumors and Metastases Leads to Up-Regulation of Their Targets Egr1, G3bp1, Hmga2 and Bach1

Expression of miRNAs in Neuroendocrine Neoplasms (NEN) is poorly characterized. We therefore wanted to examine the miRNA expression in Neuroendocrine Tumors (NETs), and identify their targets and importance in NET carcinogenesis. miRNA expression in six NEN primary tumors, six NEN metastases and fou...

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Detalles Bibliográficos
Autores principales: Døssing, Kristina B. V., Binderup, Tina, Kaczkowski, Bogumil, Jacobsen, Anders, Rossing, Maria, Winther, Ole, Federspiel, Birgitte, Knigge, Ulrich, Kjær, Andreas, Friis-Hansen, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377830/
https://www.ncbi.nlm.nih.gov/pubmed/25546138
http://dx.doi.org/10.3390/genes6010001