The Role of Genotypes That Modify the Toxicity of Chemical Mutagens in the Risk for Myeloproliferative Neoplasms

Background: The etiology of myeloproliferative neoplasms (MPN) (polycythemia vera; essential thrombocythemia; primary myelofibrosis) is unknown, however they are associated with a somatic mutation—JAK2 V617F—suggesting a potential role for environmental mutagens. Methods: We conducted a population-b...

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Detalles Bibliográficos
Autores principales: Gross-Davis, Carol Ann, Heavner, Karyn, Frank, Arthur L., Newschaffer, Craig, Klotz, Judith, Santella, Regina M., Burstyn, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377912/
https://www.ncbi.nlm.nih.gov/pubmed/25719551
http://dx.doi.org/10.3390/ijerph120302465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377912/
https://www.ncbi.nlm.nih.gov/pubmed/25719551
http://dx.doi.org/10.3390/ijerph120302465

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