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The Marine Metabolite SZ-685C Induces Apoptosis in Primary Human Nonfunctioning Pituitary Adenoma Cells by Inhibition of the Akt Pathway in Vitro

Nonfunctioning pituitary adenoma (NFPA) is one of the most common types of pituitary adenoma. The marine anthraquinone derivative SZ-685C has been isolated from the secondary metabolites of the mangrove endophytic fungus Halorosellinia sp. (No. 1403) which is found in the South China Sea. Recent res...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Tan, Ting, Mao, Zhi-Gang, Lei, Ni, Wang, Zong-Ming, Hu, Bin, Chen, Zhi-Yong, She, Zhi-Gang, Zhu, Yong-Hong, Wang, Hai-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378000/
https://www.ncbi.nlm.nih.gov/pubmed/25806467
http://dx.doi.org/10.3390/md13031569