Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus

In many cells, mRNAs containing inverted repeated Alu elements (IRAlus) in their 3′ untranslated regions (UTRs) are inefficiently exported to the cytoplasm. Such nuclear retention correlates with paraspeckle-associated protein complexes containing p54(nrb). However, nuclear retention of mRNAs contai...

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Detalles Bibliográficos
Autores principales: Hu, Shi-Bin, Xiang, Jian-Feng, Li, Xiang, Xu, Yefen, Xue, Wei, Huang, Min, Wong, Catharine C., Sagum, Cari A., Bedford, Mark T., Yang, Li, Cheng, Donghang, Chen, Ling-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378195/
https://www.ncbi.nlm.nih.gov/pubmed/25792598
http://dx.doi.org/10.1101/gad.257048.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378195/
https://www.ncbi.nlm.nih.gov/pubmed/25792598
http://dx.doi.org/10.1101/gad.257048.114

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