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Association between CHEK2 H371Y mutation and response to neoadjuvant chemotherapy in women with breast cancer

BACKGROUND: Our previous study suggested that the recurrent CHEK2 H371Y mutation is a novel pathogenic mutation that confers an increased risk of breast cancer. The purpose of this study was to investigate whether breast cancer patients with CHEK2 H371Y mutation were more likely to respond to neoadj...

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Detalles Bibliográficos
Autores principales: Liu, Yin, Xu, Ye, Ouyang, Tao, Li, Jinfeng, Wang, Tianfeng, Fan, Zhaoqing, Fan, Tie, Lin, Benyao, Xie, Yuntao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378224/
https://www.ncbi.nlm.nih.gov/pubmed/25884806
http://dx.doi.org/10.1186/s12885-015-1203-3