Type 1 interferon gene transfer enhances host defense against pulmonary Streptococcus pneumoniae infection via activating innate leukocytes

Pneumococcal infections are the leading cause of community-acquired pneumonia. Although the type 1 interferon-α (IFN-α) is a well-known antiviral cytokine, the role of IFN-α in antipneumococcal host defense and its therapeutic potential remain poorly understood. We have investigated these issues by...

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Detalles Bibliográficos
Autores principales: Damjanovic, Daniela, Khera, Amandeep, Medina, Maria Fe, Ennis, Jane, Turner, Jeffrey D, Gauldie, Jack, Xing, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378291/
https://www.ncbi.nlm.nih.gov/pubmed/26015944
http://dx.doi.org/10.1038/mtm.2014.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378291/
https://www.ncbi.nlm.nih.gov/pubmed/26015944
http://dx.doi.org/10.1038/mtm.2014.5

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