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Type 1 interferon gene transfer enhances host defense against pulmonary Streptococcus pneumoniae infection via activating innate leukocytes
Pneumococcal infections are the leading cause of community-acquired pneumonia. Although the type 1 interferon-α (IFN-α) is a well-known antiviral cytokine, the role of IFN-α in antipneumococcal host defense and its therapeutic potential remain poorly understood. We have investigated these issues by...
Autores principales: | Damjanovic, Daniela, Khera, Amandeep, Medina, Maria Fe, Ennis, Jane, Turner, Jeffrey D, Gauldie, Jack, Xing, Zhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378291/ https://www.ncbi.nlm.nih.gov/pubmed/26015944 http://dx.doi.org/10.1038/mtm.2014.5 |
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