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Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior

Farnesoid X receptor (FXR) is a nuclear hormone receptor involved in bile acid synthesis and homeostasis. Dysfunction of FXR is involved in cholestasis and atherosclerosis. FXR is prevalent in liver, gallbladder, and intestine, but it is not yet clear whether it modulates neurobehavior. In the curre...

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Detalles Bibliográficos
Autores principales: Huang, Fei, Wang, Tingting, Lan, Yunyi, Yang, Li, Pan, Weihong, Zhu, Yonghui, Lv, Boyang, Wei, Yuting, Shi, Hailian, Wu, Hui, Zhang, Beibei, Wang, Jie, Duan, Xiaofeng, Hu, Zhibi, Wu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378301/
https://www.ncbi.nlm.nih.gov/pubmed/25870546
http://dx.doi.org/10.3389/fnbeh.2015.00070