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RNA-Seq gene expression profiling of HepG2 cells: the influence of experimental factors and comparison with liver tissue

BACKGROUND: Human hepatoma HepG2 cells are used as an in vitro model of the human liver. High-throughput transcriptomic sequencing is an advanced approach for assessing the functional state of a tissue or cell type. However, the influence of experimental factors, such as the sample preparation metho...

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Detalles Bibliográficos
Autores principales: Tyakht, Alexander V, Ilina, Elena N, Alexeev, Dmitry G, Ischenko, Dmitry S, Gorbachev, Alexey Y, Semashko, Tatiana A, Larin, Andrei K, Selezneva, Oksana V, Kostryukova, Elena S, Karalkin, Pavel A, Vakhrushev, Igor V, Kurbatov, Leonid K, Archakov, Alexander I, Govorun, Vadim M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378340/
https://www.ncbi.nlm.nih.gov/pubmed/25511409
http://dx.doi.org/10.1186/1471-2164-15-1108