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Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs

The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs. Inoculation did not cause disease and vaccine virus shedding was minimal, which indicated that...

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Detalles Bibliográficos
Autores principales: de Wit, Emmie, Marzi, Andrea, Bushmaker, Trenton, Brining, Doug, Scott, Dana, Richt, Juergen A., Geisbert, Thomas W., Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378486/
https://www.ncbi.nlm.nih.gov/pubmed/25811738
http://dx.doi.org/10.3201/eid2104.142012