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Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner
BACKGROUND: Activation of microglia plays a crucial role in immune and inflammatory processes after ischemic stroke. Microglia is reported with two opposing activated phenotypes, namely, classic phenotype (M1) and the alternative phenotype (M2). Inhibiting M1 while stimulating M2 has been suggested...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378556/ https://www.ncbi.nlm.nih.gov/pubmed/25889216 http://dx.doi.org/10.1186/s12974-015-0270-3 |