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Reliable cell cycle commitment in budding yeast is ensured by signal integration

Cell fate decisions are critical for life, yet little is known about how their reliability is achieved when signals are noisy and fluctuating with time. In this study, we show that in budding yeast, the decision of cell cycle commitment (Start) is determined by the time integration of its triggering...

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Detalles Bibliográficos
Autores principales: Liu, Xili, Wang, Xin, Yang, Xiaojing, Liu, Sen, Jiang, Lingli, Qu, Yimiao, Hu, Lufeng, Ouyang, Qi, Tang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378612/
https://www.ncbi.nlm.nih.gov/pubmed/25590650
http://dx.doi.org/10.7554/eLife.03977