The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway

The exosome and its nuclear specific subunit Rrp6 form a 3’-5’ exonuclease complex that regulates diverse aspects of RNA biology including 3’ end processing and degradation of a variety of noncoding RNAs (ncRNAs) and unstable transcripts. Known targets of the nuclear exosome include short (<1000...

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Detalles Bibliográficos
Autores principales: Fox, Melanie J., Gao, Hongyu, Smith-Kinnaman, Whitney R., Liu, Yunlong, Mosley, Amber L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378619/
https://www.ncbi.nlm.nih.gov/pubmed/25680078
http://dx.doi.org/10.1371/journal.pgen.1004999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378619/
https://www.ncbi.nlm.nih.gov/pubmed/25680078
http://dx.doi.org/10.1371/journal.pgen.1004999

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