Role of intracellular tyrosines in activating KIT induced myeloproliferative disease

Gain-of-function mutations in KIT receptor in humans are associated with gastrointestinal stromal tumors (GIST), systemic mastocytosis (SM), and acute myelogenous leukemia (AML). The intracellular signals that contribute to oncogenic KIT induced myeloproliferative disease (MPD) are poorly understood...

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Detalles Bibliográficos
Autores principales: Ma, Peilin, Mali, Raghuveer Singh, Martin, Holly, Ramdas, Baskar, Sims, Emily, Kapur, Reuben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378686/
https://www.ncbi.nlm.nih.gov/pubmed/22297723
http://dx.doi.org/10.1038/leu.2012.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378686/
https://www.ncbi.nlm.nih.gov/pubmed/22297723
http://dx.doi.org/10.1038/leu.2012.22

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