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Novel Mechanism of Arenavirus-Induced Liver Pathology

Viral hemorrhagic fevers (VHFs) encompass a group of diseases with cardinal symptoms of fever, hemorrhage, and shock. The liver is a critical mediator of VHF disease pathogenesis and high levels of ALT/AST transaminases in plasma correlate with poor prognosis. In fact, Lassa Fever (LF), the most pre...

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Detalles Bibliográficos
Autores principales: Beier, Juliane I., Jokinen, Jenny D., Holz, Gretchen E., Whang, Patrick S., Martin, Amah M., Warner, Nikole L., Arteel, Gavin E., Lukashevich, Igor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378851/
https://www.ncbi.nlm.nih.gov/pubmed/25822203
http://dx.doi.org/10.1371/journal.pone.0122839