Inhibition of Telomere Recombination by Inactivation of KEOPS Subunit Cgi121 Promotes Cell Longevity

DNA double strand break (DSB) is one of the major damages that cause genome instability and cellular aging. The homologous recombination (HR)-mediated repair of DSBs plays an essential role in assurance of genome stability and cell longevity. Telomeres resemble DSBs and are competent for HR. Here we...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Jing, He, Ming-Hong, Duan, Yi-Ming, Liu, Yu-Ting, Zhou, Jin-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378880/
https://www.ncbi.nlm.nih.gov/pubmed/25822194
http://dx.doi.org/10.1371/journal.pgen.1005071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378880/
https://www.ncbi.nlm.nih.gov/pubmed/25822194
http://dx.doi.org/10.1371/journal.pgen.1005071

Ejemplares similares