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Role of swi7H4 Mutant Allele of DNA Polymerase α in the DNA Damage Checkpoint Response
Besides being a mediator of initiation of DNA replication, DNA polymerase α plays a key role in chromosome maintenance. Swi7H4, a novel temperature sensitive mutant of DNA polymerase α was shown to be defective in transcriptional silencing at the mating type centromere and telomere loci. It is also...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378889/ https://www.ncbi.nlm.nih.gov/pubmed/25822347 http://dx.doi.org/10.1371/journal.pone.0124063 |