Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity

Spinal muscular atrophy (SMA) is a monogenic neurodegenerative disorder subdivided into four different types. Whole genome methylation analysis revealed 40 CpG sites associated with genes that are significantly differentially methylated between SMA patients and healthy individuals of the same age. T...

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Detalles Bibliográficos
Autores principales: Zheleznyakova, Galina Yu., Nilsson, Emil K., Kiselev, Anton V., Maretina, Marianna A., Tishchenko, Lyudmila I., Fredriksson, Robert, Baranov, Vladislav S., Schiöth, Helgi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378931/
https://www.ncbi.nlm.nih.gov/pubmed/25821969
http://dx.doi.org/10.1371/journal.pone.0121964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378931/
https://www.ncbi.nlm.nih.gov/pubmed/25821969
http://dx.doi.org/10.1371/journal.pone.0121964

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