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Expression of 1N3R-Tau Isoform Inhibits Cell Proliferation by Inducing S Phase Arrest in N2a Cells

Tau is a microtubule-associated protein implicated in neurodegenerative tauopathies. Six tau isoforms are generated from a single gene through alternative splicing of exons 2, 3 and 10 in human brain. Differential expression of tau isoforms has been detected in different brain areas, during neurodev...

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Detalles Bibliográficos
Autores principales: Li, Li, Xu, Zhi-Peng, Liu, Gong-Ping, Xu, Cheng, Wang, Zhi-Hao, Li, Xiao-Guang, Liu, En-Jie, Zeng, Juan, Chai, Da-Min, Yao, Wen-Long, Wang, Jian-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378987/
https://www.ncbi.nlm.nih.gov/pubmed/25822823
http://dx.doi.org/10.1371/journal.pone.0119865